Immune cell	Biomarker	Correlation coefficient	P value
B cell	CD19	0.135	**
	CD20(KRT20)	0.169	**
	CD38	0.033	0.525
CD8+ T cell	CD8A	0.021	0.682
	CD8B	0.034	0.516
Tfh	BCL6	0.235	***
	ICOS	0.116	*
	CXCR5	0.020	0.705
Th1	T-bet(TBX21)	-0.090	0.0837
	STAT1	0.087	0.0931
	STAT4	0.01	0.849
	IL12RB2	0.062	0.232
	WSX1(IL27RA)	0.368	***
	IFN-γ(IFNG)	0.107	*
	TNF-α(TNF)	0.089	0.0882
Th2	CCR3	0.248	***
	GATA3	0.028	0.596
	STAT5A	0.199	***
	STAT6	0.135	**
Th9	IRF4	0.077	0.138
	PU.1(SPI1)	0.134	**
	TGFBR2	-0.087	0.0942
Th17	IL-17A	-0.023	0.655
	IL-21R	0.103	*
	IL-23R	0.124	*
	STAT3	0.152	**
Th22	AHR	0.065	0.215
	CCR10	0.296	***
Treg	CCR8	0.107	*
	CD25(IL2RA)	0.184	***
	FOXP3	-0.106	*
M1 macrophage	COX2(PTGS2)	0.055	0.287
	INOS(NOS2)	-0.11	*
	IRF5	0.203	***
M2 macrophage	ARG1	-0.208	***
	CD206(MRC1)	-0.141	**
	CD115(CSF1R)	0.085	0.103
TAM	PDCD1LG2	-0.025	0.631
	CD80	0.161	**
	CD40	0.099	0.0578
	TLR7	0.062	0.236
Nature killer cell	CD7	0.174	***
	KIR3DL1	-0.005	0.918
	XCL1	0.165	**
Neutrophil	CD11b(ITGAM)	0.246	***
	CD15(FUT4)	0.217	***
	CD66b(CEACAM8)	-0.009	0.862
Dendritic cell	CD1C	-0.138	**
	CD11c(ITGAX)	0.146	**
	CD141(THBD)	-0.185	***
Tfh for Follicular helper T cell, Th for T helper cell, Treg for Regulatory T cell, TAM for Tumor-associated macrophage. *P<0.05, **P<0.01, ***P<0.001.