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International Journal of Biomedical Science
4(2) 130-134
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© 2005 Master Publishing Group
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Original Article
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Changes in Mice Brain Spontaneous Electrical Activity during Cortical Spreading Depression due to Mobile Phone Radiation |
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Samera M. Sallam1, Ehab I. Mohamed2, Abdel-Fattah B. Dawood1 |
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1 Department of Physics, Faculty of Science, University of Benha, Benha, Egypt;
2 Department of Medical Biophysics, Medical Research Institute, University of Alexandria, Alexandria, Egypt
Corresponding Author: Prof. Ehab I. Mohamed, Department of Medical Biophysics, Medical Research Institute, University of Alexandria, 165 El Horreya Avenue, 21561 Alexandria, Egypt. Tel: (+20) 3 428 2331/ 2373/ 3543/ 5455; Fax: (+20) 3 428 3719; Mobile: (+20) 12 932 2010; E-mail: eimohamed@yahoo.com.
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EEG spontaneous activity; cortical spreading depression; mice brain; mobile phone; microwave radiation; slow potential changes |
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The objective of the present study was to investigate changes in spontaneous EEG activity during cortical spreading depression (CSD) in mice brain. The cortical region of anaesthetized mice were exposed to the electromagnetic fields (EMFs) emitted from a mobile phone (MP, 935.2 - 960.2 MHz, 41.8 mW/cm2). The effect of EMFs on EEG was investigated before and after exposure to different stimuli (MP, 2% KCl, and MP & 2% KCl). The records of brain spontaneous EEG activity, slow potential changes (SPC), and spindle shaped firings were obtained through an interfaced computer. The results showed increases in the amplitude of evoked spindles by about 87%, 17%, and 226% for MP, 2% KCl, and MP & 2% KCl; respectively, as compared to values for the control group. These results showed that the evoked spindle is a more sensitive indicator of the effect of exposure to EMFs from MP.
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